Cnpy3^tm1Kmiy
Targeted Allele Detail

Summary

• Symbol: Cnpy3^tm1Kmiy
• Name: canopy FGF signaling regulator 3; targeted mutation 1, Kensuke Miyake
• MGI ID: MGI:3767622
• Synonyms: PRAT4A^-
• Gene: Cnpy3 Location: Chr17:47046631-47063140 bp, - strand Genetic Position: Chr17, 22.9 cM, cytoband C
• Alliance: Cnpy3^tm1Kmiy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:128513
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Exon 1 was replaced by a neo cassette. The absence of protein was confirmed by western blot analysis on splenic cell protein extracts. (J:128513)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cnpy3 Mutation: 16 strains or lines available

References

• Original: J:128513 Takahashi K, et al., A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses. J Exp Med. 2007 Nov 26;204(12):2963-76
• All: 4 reference(s)