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Tg(CAG-AR*24Q)5-5Sobue
Transgene Detail
Summary
Symbol: Tg(CAG-AR*24Q)5-5Sobue
Name: transgene insertion 5-5, Gen Sobue
MGI ID: MGI:3767715
Synonyms: AR-24Q, Tg(ACTB-AR*24Q)5-5Sobu
Transgene: Tg(CAG-AR*24Q)5-5Sobue  Location: unknown  
Alliance: Tg(CAG-AR*24Q)5-5Sobue page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CAG-AR*24Q)5-5Sobue expresses 1 gene
 
Mutation detailsThe chicken actin promoter with a CMV enhancer (CAGGS) was used to drive the expression of a human androgen receptor open reading frame that contained a block of 24 CAG repeats. (J:128619)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
Three lines were created (5-5, 8-7, 12-13) with copy numbers of the transgene ranging from 1 to 5. Lines are phenotypically identical and line 5-5 was selected as the representative line.
References
Original:  J:128619 Katsuno M, et al., Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy. Neuron. 2002 Aug 29;35(5):843-54
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory