Tg(THY1-SNCA)1Sud
Transgene Detail

Summary

• Symbol: Tg(THY1-SNCA)1Sud
• Name: transgene insertion 1, Thomas C Sudhof
• MGI ID: MGI:3767987
• Synonyms: LHS, Syn^htg, tSyn
• Transgene: Tg(THY1-SNCA)1Sud Location: unknown
• Alliance: Tg(THY1-SNCA)1Sud page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(THY1-SNCA)1Sud expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SNCA (6622)

  Snca	(MGI:1277151)

• Tg(THY1-SNCA)1Sud expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  THY1 (7070)

  Thy1	(MGI:98747)

• Mutation details: The transgene expresses the human SNCA (synuclein, alpha) gene under the control of a human THY1 (thymus cell antigen 1, theta) promoter. (J:115193)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:115193 Chandra S, et al., Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration. Cell. 2005 Nov 4;123(3):383-96
• All: 6 reference(s)