Tg(THY1-SNCA*A53T)M53Sud
Transgene Detail

Summary

• Symbol: Tg(THY1-SNCA*A53T)M53Sud
• Name: transgene insertion M53, Thomas C Sudhof
• MGI ID: MGI:3768388
• Synonyms: M53, M70A53T, Tg(THY1-SNCA*A53T)1Sud
• Transgene: Tg(THY1-SNCA*A53T)M53Sud Location: unknown
• Alliance: Tg(THY1-SNCA*A53T)M53Sud page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(THY1-SNCA*A53T)M53Sud expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SNCA (6622)

  Snca	(MGI:1277151)

• Mutation details: This transgenic strain carries the mouse Snca (synuclein, alpha) gene under the control of a human THY1 (thymus cell antigen 1, theta) promoter. (J:115193)

Disease models

Expression

In Structures Affected by this Mutation:

12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:115193 Chandra S, et al., Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration. Cell. 2005 Nov 4;123(3):383-96
• All: 14 reference(s)