Pdgfc^tm1Hdin
Targeted Allele Detail

Summary

• Symbol: Pdgfc^tm1Hdin
• Name: platelet-derived growth factor, C polypeptide; targeted mutation 1, Hao Ding
• MGI ID: MGI:3768436
• Synonyms: Pdgf-c^flox
• Gene: Pdgfc Location: Chr3:80943723-81121347 bp, + strand Genetic Position: Chr3, 35.73 cM
• Alliance: Pdgfc^tm1Hdin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:128709
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 5 was replaced with an SA-IRESbetageo cassette flanked by FRT sites and an exon 5 flanked by loxP sites. The SA-IRESbetageo cassette was removed by flp-mediated recombination. (J:128709)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdgfc Mutation: 35 strains or lines available

References

• Original: J:128709 Wu X, et al., Generation of conditional knockout alleles for PDGF-C. Genesis. 2007 Oct;45(10):653-7
• All: 1 reference(s)