Twist1^tm2.1Bhr
Targeted Allele Detail

Summary

• Symbol: Twist1^tm2.1Bhr
• Name: twist basic helix-loop-helix transcription factor 1; targeted mutation 2.1, Richard R Behringer
• MGI ID: MGI:3768519
• Synonyms: Twist1^deltaEx1
• Gene: Twist1 Location: Chr12:34007670-34009828 bp, + strand Genetic Position: Chr12, 14.81 cM, cytoband B-C1
• Alliance: Twist1^tm2.1Bhr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:128714
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• The open reading frame was removed by cre-mediated recombination to create a null allele. (J:128714)

Expression

In Mice Carrying this Mutation:	37 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Twist1 Mutation: 18 strains or lines available

References

• Original: J:128714 Chen YT, et al., Generation of a Twist1 conditional null allele in the mouse. Genesis. 2007 Sep;45(9):588-92
• All: 3 reference(s)