Fgf12^tm1Gol
Targeted Allele Detail

Summary

• Symbol: Fgf12^tm1Gol
• Name: fibroblast growth factor 12; targeted mutation 1, Mitchell Goldfarb
• MGI ID: MGI:3768545
• Synonyms: Fhf1^-
• Gene: Fgf12 Location: Chr16:27978850-28571820 bp, - strand Genetic Position: Chr16, 19.38 cM, cytoband B1-B3
• Alliance: Fgf12^tm1Gol page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:128732
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 2 was replaced with a neo cassette. Authors state that this is a null allele. (J:128732)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf12 Mutation: 16 strains or lines available

References

• Original: J:128732 Goldfarb M, et al., Fibroblast growth factor homologous factors control neuronal excitability through modulation of voltage-gated sodium channels. Neuron. 2007 Aug 2;55(3):449-63
• All: 2 reference(s)