Errfi1^tm1.1Jwj
Targeted Allele Detail

Summary

• Symbol: Errfi1^tm1.1Jwj
• Name: ERBB receptor feedback inhibitor 1; targeted mutation 1.1, Jae-Wook Jeong
• MGI ID: MGI:3769411
• Synonyms: Errfi^d, Mig-6^-
• Gene: Errfi1 Location: Chr4:150938376-150953349 bp, + strand Genetic Position: Chr4, 81.5 cM, cytoband E1
• Alliance: Errfi1^tm1.1Jwj page

Epidermal hyperplasia in Errfi1^tm1.1Jwj/Errfi1^tm1.1Jwj mice

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:129106
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The coding alleles 2 through 4 were removed by cre-mediated recombination. The absence of protein product was confirmed by western blot analysis on liver, lung, uterus and skin extracts. (J:129106)

Expression

In Mice Carrying this Mutation:	32 assay results
In Structures Affected by this Mutation:	12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Errfi1 Mutation: 18 strains or lines available

References

• Original: J:129106 Jin N, et al., Generation of a Mig-6 conditional null allele. Genesis. 2007 Nov;45(11):716-21
• All: 7 reference(s)