Cadm1^tm1Momo
Targeted Allele Detail

Summary

• Symbol: Cadm1^tm1Momo
• Name: cell adhesion molecule 1; targeted mutation 1, Takashi Momoi
• MGI ID: MGI:3769418
• Synonyms: Ra175^-, SynCAM 1 KO
• Gene: Cadm1 Location: Chr9:47441471-47769413 bp, + strand Genetic Position: Chr9, 25.83 cM, cytoband B-C
• Alliance: Cadm1^tm1Momo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:129496
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 and part of intron 1 were replaced with a lacZ-neo cassette. X-galactosidase staining was performed to confirm lacZ expression. (J:129496)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Cadm1 Mutation: 40 strains or lines available

References

• Original: J:129496 Fujita E, et al., Oligo-astheno-teratozoospermia in mice lacking RA175/TSLC1/SynCAM/IGSF4A, a cell adhesion molecule in the immunoglobulin superfamily. Mol Cell Biol. 2006 Jan;26(2):718-26
• All: 20 reference(s)