Tbx3^tm1Jcib
Targeted Allele Detail

Summary

• Symbol: Tbx3^tm1Jcib
• Name: T-box 3; targeted mutation 1, Juan Carlos Belmonte
• MGI ID: MGI:3769504
• Synonyms: Tbx3^neo
• Gene: Tbx3 Location: Chr5:119808734-119822789 bp, + strand Genetic Position: Chr5, 60.34 cM
• Alliance: Tbx3^tm1Jcib page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:129349
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Part of exon 1 was replaced with a neo cassette with several stop codons. (J:129349)

Expression

In Mice Carrying this Mutation:	11 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbx3 Mutation: 49 strains or lines available

References

• Original: J:129349 Ribeiro I, et al., Tbx2 and Tbx3 regulate the dynamics of cell proliferation during heart remodeling. PLoS One. 2007;2(4):e398
• All: 2 reference(s)