Msx2^tm1Rem
Targeted Allele Detail

Summary

• Symbol: Msx2^tm1Rem
• Name: msh homeobox 2; targeted mutation 1, Robert Maxson
• MGI ID: MGI:3769672
• Synonyms: Msx2^flox
• Gene: Msx2 Location: Chr13:53620917-53626816 bp, - strand Genetic Position: Chr13, 27.84 cM
• Alliance: Msx2^tm1Rem page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:128624
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed and frt-flanked neo cassette was inserted into intron 1 and an additional loxP site was inserted in intron 2. The neo cassette was removed by flp-mediated recombination (J:128624)

Expression

In Mice Carrying this Mutation:	4 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Msx2 Mutation: 23 strains or lines available

References

• Original: J:128624 Fu H, et al., Conditional alleles of Msx1 and Msx2. Genesis. 2007 Aug;45(8):477-81
• All: 14 reference(s)