Tg(RSV-BDKRB2)8905Chao
Transgene Detail

Summary

• Symbol: Tg(RSV-BDKRB2)8905Chao
• Name: transgene insertion 8905, Julie Chao
• MGI ID: MGI:3769677
• Synonyms: RSV-cHBKR
• Transgene: Tg(RSV-BDKRB2)8905Chao Location: unknown
• Alliance: Tg(RSV-BDKRB2)8905Chao page

Transgene origin

• Strain of Origin: C57BL/6 x DBA/2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(RSV-BDKRB2)8905Chao expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  BDKRB2 (624)

  Bdkrb2

  (MGI:102845)

• Mutation details: The RSV-LTR enchancer/promoter was used to drive expression of the human BDKRB2 open reading frame in the aorta, brain, heart, lung, liver, kidney, uterus and prostate gland. (J:128651)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Lines 8905 and 9830 were created with line 9830 exhibiting higher transgene copy number. Both lines exhibit identical phenotypes.

References

• Original: J:128651 Wang DZ, et al., Hypotension in transgenic mice overexpressing human bradykinin B2 receptor. Hypertension. 1997 Jan;29(1 Pt 2):488-93
• All: 1 reference(s)