Tg(Thy1-cmyc)6LKio
Transgene Detail

Summary

• Symbol: Tg(Thy1-cmyc)6LKio
• Name: transgene insertion 6L, Dimitris Kioussis
• MGI ID: MGI:3770123
• Transgene: Tg(Thy1-cmyc)6LKio Location: unknown
• Alliance: Tg(Thy1-cmyc)6LKio page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Thy1-cmyc)6LKio expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Myc (MGI:97250)

• Mutation details: The two coding exons of cmyc were inserted into intron 1 of Thy1 to create a transgene that expressed cmyc under the Thy1 promoter. (J:129440)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

13 lines were created with copy numbers ranging from 1 to 20. Lines 1, 28 and 29 have identical phenotypes. Lines 7 and 6L contain low copy numbers of the transgene and exhibit identical phenotypes. Lines 6 and 25 exhibit identical phenotypes.

References

• Original: J:129440 Spanopoulou E, et al., Complex lymphoid and epithelial thymic tumours in Thy1-myc transgenic mice. Nature. 1989 Nov 9;342(6246):185-9
• All: 1 reference(s)