Bdnf^tm1Limm
Targeted Allele Detail

Summary

• Symbol: Bdnf^tm1Limm
• Name: brain derived neurotrophic factor; targeted mutation 1, Lisa M Monteggia
• MGI ID: MGI:3770141
• Gene: Bdnf Location: Chr2:109505045-109557352 bp, + strand Genetic Position: Chr2, 56.63 cM
• Alliance: Bdnf^tm1Limm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:129526
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A neo cassette with a 3' loxP site was inserted into intron 6 and an additional loxP site was inserted into intron 5. (J:129526)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bdnf Mutation: 42 strains or lines available

References

• Original: J:129526 Monteggia LM, et al., Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors. Biol Psychiatry. 2007 Jan 15;61(2):187-97
• All: 3 reference(s)