Pbx1^tm1.1Febe
Targeted Allele Detail

Summary

• Symbol: Pbx1^tm1.1Febe
• Name: pre B cell leukemia homeobox 1; targeted mutation 1.1, Felix Beuschlein
• MGI ID: MGI:3770151
• Synonyms: Pbx1^-
• Gene: Pbx1 Location: Chr1:167946933-168259839 bp, - strand Genetic Position: Chr1, 75.95 cM
• Alliance: Pbx1^tm1.1Febe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:129552
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A floxed neo cassette was inserted into intron 5 and an additional loxP site was inserted into intron 6. The neo cassette and exon 6 were subsequently removed by cre-mediated recombination using a transiently expressing cre plasmid. (J:129552)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pbx1 Mutation: 40 strains or lines available

References

• Original: J:129552 Lichtenauer UD, et al., Pre-B-cell transcription factor 1 and steroidogenic factor 1 synergistically regulate adrenocortical growth and steroidogenesis. Endocrinology. 2007 Feb;148(2):693-704
• All: 1 reference(s)