Nuak1^tm1Sia
Targeted Allele Detail

Summary

• Symbol: Nuak1^tm1Sia
• Name: NUAK family, SNF1-like kinase, 1; targeted mutation 1, Shinichi Aizawa
• MGI ID: MGI:3770654
• Synonyms: Omphk1^lacZ
• Gene: Nuak1 Location: Chr10:84206769-84276461 bp, - strand Genetic Position: Chr10, 41.42 cM
• Alliance: Nuak1^tm1Sia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110717
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A lacZ cassette with a neo cassette was inserted just upstream of the translation initiation site. The absence of the transcript was confirmed by RT-PCR analysis on E9.5 embryos, indicating that this is a null mutation. (J:110717)

Expression

In Mice Carrying this Mutation:	96 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nuak1 Mutation: 44 strains or lines available

References

• Original: J:110717 Hirano M, et al., A new serine/threonine protein kinase, Omphk1, essential to ventral body wall formation. Dev Dyn. 2006 Aug;235(8):2229-37
• All: 6 reference(s)