Pycardtm1Nnz
Targeted Allele Detail
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| Symbol: |
Pycardtm1Nnz |
| Name: |
PYD and CARD domain containing; targeted mutation 1, Gabriel Nunez |
| MGI ID: |
MGI:3771030 |
| Synonyms: |
Asc- |
| Gene: |
Pycard Location: Chr7:127590545-127593039 bp, - strand Genetic Position: Chr7, 69.88 cM, cytoband F4
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| Alliance: |
Pycardtm1Nnz page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:129871
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The coding exons of the gene were replaced with beta-galactosidase and neomycin resistance genes. Gene inactivation was confirmed by western blot on spleen and bone marrow from homozygous mice.
(J:129871)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Pycard Mutation: |
15 strains or lines available
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| Original: |
J:129871 Ozoren N, et al., Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes. J Immunol. 2006 Apr 1;176(7):4337-42 |
| All: |
45 reference(s) |
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Analysis Tools
