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Gpihbp1tm1Sgy
Targeted Allele Detail
Summary
Symbol: Gpihbp1tm1Sgy
Name: GPI-anchored HDL-binding protein 1; targeted mutation 1, Stephen G Young
MGI ID: MGI:3771171
Synonyms: Gpihbp1-, Gpihbp1tm1Sgyo
Gene: Gpihbp1  Location: Chr15:75468479-75470062 bp, + strand  Genetic Position: Chr15, 34.59 cM, cytoband E1
Alliance: Gpihbp1tm1Sgy page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:129764
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe open reading frame was replaced with a lacZ-neo cassette. The absence of protein product was confirmed by western blot analysis on gonadal fat and brown adipose tissue extracts. However, no beta-galactosidase activity could be detected. (J:129764)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gpihbp1 Mutation:  20 strains or lines available
References
Original:  J:129764 Beigneux AP, et al., Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons. Cell Metab. 2007 Apr;5(4):279-91
All:  24 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory