Slc17a6^tm1Lowl
Targeted Allele Detail

Summary

• Symbol: Slc17a6^tm1Lowl
• Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6; targeted mutation 1, Bradford B Lowell
• MGI ID: MGI:3771177
• Synonyms: Vglut2^flox
• Gene: Slc17a6 Location: Chr7:51271754-51320867 bp, + strand Genetic Position: Chr7, 32.78 cM, cytoband B4
• Alliance: Slc17a6^tm1Lowl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:129860
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Lox P sites were inserted upstream and downstream of exon 2. A neo cassette used for selection purposes was removed by flp-mediated recombination. (J:129860)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Slc17a6 Mutation: 60 strains or lines available

References

• Original: J:129860 Tong Q, et al., Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia. Cell Metab. 2007 May;5(5):383-93
• All: 45 reference(s)