Slc17a6^tm1.1Lowl
Targeted Allele Detail

Summary

• Symbol: Slc17a6^tm1.1Lowl
• Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6; targeted mutation 1.1, Bradford B Lowell
• MGI ID: MGI:3771178
• Synonyms: Vglut2^-
• Gene: Slc17a6 Location: Chr7:51271754-51320867 bp, + strand Genetic Position: Chr7, 32.78 cM, cytoband B4
• Alliance: Slc17a6^tm1.1Lowl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:129860
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Germ-line cre-mediated recombination was used to delete exon 2 resulting in a frame shift that leads to a null allele. (J:129860)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc17a6 Mutation: 60 strains or lines available

References

• Original: J:129860 Tong Q, et al., Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia. Cell Metab. 2007 May;5(5):383-93
• All: 1 reference(s)