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Ppytm1Mws
Targeted Allele Detail
Summary
Symbol: Ppytm1Mws
Name: pancreatic polypeptide; targeted mutations 1, Mark W Sleeman
MGI ID: MGI:3771719
Synonyms: Ppy-
Gene: Ppy  Location: Chr11:101990757-101992145 bp, - strand  Genetic Position: Chr11, 65.48 cM
Alliance: Ppytm1Mws page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130105
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA lacZ and neo cassette was inserted after the translation initiation site in exon 2 and replaces the remaining exons. The absence of protein product was confirmed by immunohistochemistry of pancreatic islet cells. (J:130105)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ppy Mutation:  9 strains or lines available
References
Original:  J:130105 Wortley KE, et al., Peptide YY regulates bone turnover in rodents. Gastroenterology. 2007 Nov;133(5):1534-43
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory