Phb1^{Gt(BGB069)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Phb1^{Gt(BGB069)Byg}
• Name: prohibitin 1; gene trap BGB069, BayGenomics
• MGI ID: MGI:3771852
• Gene: Phb1 Location: Chr11:95557783-95571599 bp, + strand Genetic Position: Chr11, 59.01 cM, cytoband D
• Alliance: Phb1^{Gt(BGB069)Byg} page

Mutation origin

• Mutant Cell Line: BGB069
• Germline Transmission: Earliest citation of germline transmission: J:130064
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• No molecular information is given. (J:130064)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  BGB069	CL903409 ; (MGI Seq Detail)	5' RACE	Chr11:95557835-95562371 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  5 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Phb1 Mutation: 25 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:130064 He B, et al., A repressive role for prohibitin in estrogen signaling. Mol Endocrinol. 2008 Feb;22(2):344-60
• All: 3 reference(s)