Rnf2^tm1Mvi
Targeted Allele Detail

Summary

• Symbol: Rnf2^tm1Mvi
• Name: ring finger protein 2; targeted mutation 1, Miguel Vidal
• MGI ID: MGI:3772186
• Synonyms: Ring1B^flox
• Gene: Rnf2 Location: Chr1:151345159-151376562 bp, - strand Genetic Position: Chr1, 64.15 cM
• Alliance: Rnf2^tm1Mvi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130397
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted into intron 1 and an additional loxP site was inserted upstream of exon 1. (J:130397)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rnf2 Mutation: 36 strains or lines available

References

• Original: J:130397 Cales C, et al., Inactivation of the polycomb group protein Ring1B unveils an antiproliferative role in hematopoietic cell expansion and cooperation with tumorigenesis associated with Ink4a deletion. Mol Cell Biol. 2008 Feb;28(3):1018-28
• All: 35 reference(s)