Rtel1^tm1Hdin
Targeted Allele Detail

Summary

• Symbol: Rtel1^tm1Hdin
• Name: regulator of telomere elongation helicase 1; targeted mutation 1, Hao Ding
• MGI ID: MGI:3772370
• Synonyms: Rtel^flox
• Gene: Rtel1 Location: Chr2:180961532-180998409 bp, + strand Genetic Position: Chr2, 103.63 cM
• Alliance: Rtel1^tm1Hdin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130490
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 7 was replaced by an FRT-flanked beta-geo cassette and a floxed exon 7. The beta-geo cassette was removed by flp-mediated recombination. (J:130490)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rtel1 Mutation: 75 strains or lines available

References

• Original: J:130490 Wu X, et al., Establishment of conditional knockout alleles for the gene encoding the regulator of telomere length (RTEL). Genesis. 2007 Dec;45(12):788-92
• All: 6 reference(s)