Tor1a^tm2.1Yql
Targeted Allele Detail

Summary

• Symbol: Tor1a^tm2.1Yql
• Name: torsin family 1, member A (torsin A); targeted mutation 2.1, Yuqing Li
• MGI ID: MGI:3772565
• Synonyms: Dyt1 delta
• Gene: Tor1a Location: Chr2:30850639-30857945 bp, - strand Genetic Position: Chr2, 21.77 cM
• Alliance: Tor1a^tm2.1Yql page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130483
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 3 and 4 were deleted by germ-line, cre-mediated recombination. Deletion of these exons results in the creation of a premature stop codon in exon 5 and thereby a null allele. (J:130483)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tor1a Mutation: 24 strains or lines available

References

• Original: J:130483 Yokoi F, et al., Motor Deficits and Hyperactivity in Cerebral Cortex-specific Dyt1 Conditional Knockout Mice. J Biochem. 2008 Jan;143(1):39-47
• All: 5 reference(s)