Calcrl^tm2Kmca
Targeted Allele Detail

Summary

• Symbol: Calcrl^tm2Kmca
• Name: calcitonin receptor-like; targeted mutation 2, Kathleen M Caron
• MGI ID: MGI:3772921
• Synonyms: calcrl^Flox
• Gene: Calcrl Location: Chr2:84160970-84255755 bp, - strand Genetic Position: Chr2, 49.38 cM
• Alliance: Calcrl^tm2Kmca page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130930
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An frt-flanked neo cassette with a 5' loxP site was inserted into intron 4 and an additional loxP site was inserted into intron 6. (J:130930)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Calcrl Mutation: 39 strains or lines available

References

• Original: J:130930 Fritz-Six KL, et al., Adrenomedullin signaling is necessary for murine lymphatic vascular development. J Clin Invest. 2008 Jan;118(1):40-50
• All: 7 reference(s)