Tg(tetO-Clock)1Jt
Transgene Detail

Summary

• Symbol: Tg(tetO-Clock)1Jt
• Name: transgene insertion 1, Joseph S Takahashi
• MGI ID: MGI:3772938
• Synonyms: tetO::Clock^wt, Tg(tetO-Clock)isoJt
• Transgene: Tg(tetO-Clock)1Jt Location: unknown
• Alliance: Tg(tetO-Clock)1Jt page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-Clock)1Jt expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Clock (MGI:99698)

• Mutation details: A transgenic vector was designed to carry the full-length wildtype mouse Clock gene downstream of a tetracycline-responsive promoter (TRE; tetO). Crossing these mice with mice expressing the tTA or reverse tetracycline-controlled transactivator protein under control of tissue-specific promoters, transgene expression can be regulated in appropriate tissues in the offspring with administration of the tet analog doxycycline. (J:120326)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:120326 Hong HK, et al., Inducible and reversible Clock gene expression in brain using the tTA system for the study of circadian behavior. PLoS Genet. 2007 Feb 23;3(2):e33
• All: 2 reference(s)