Sox4^tm1.1Vlf
Targeted Allele Detail

Summary

• Symbol: Sox4^tm1.1Vlf
• Name: SRY (sex determining region Y)-box 4; targeted mutation 1.1, Veronique Lefebvre
• MGI ID: MGI:3773013
• Synonyms: Sox4^fl-
• Gene: Sox4 Location: Chr13:29132902-29137682 bp, - strand Genetic Position: Chr13, 12.87 cM, cytoband A3-A5
• Alliance: Sox4^tm1.1Vlf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130461
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The coding region of the gene was removed by germ-line, cre-mediated recombination. The absence of absence of transcript was confirmed by northern blot analysis on total RNA from E12.5 embryos. (J:130461)

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox4 Mutation: 23 strains or lines available

References

• Original: J:130461 Penzo-Mendez A, et al., Generation of mice harboring a Sox4 conditional null allele. Genesis. 2007 Dec;45(12):776-80
• All: 3 reference(s)