Ptgdr2^tm1Tasa
Targeted Allele Detail

Summary

• Symbol: Ptgdr2^tm1Tasa
• Name: prostaglandin D2 receptor 2; targeted mutation 1, Takahiro Satoh
• MGI ID: MGI:3773068
• Synonyms: CRTH2^-, Gpr44^-
• Gene: Ptgdr2 Location: Chr19:10914524-10919875 bp, + strand Genetic Position: Chr19, 7.4 cM
• Alliance: Ptgdr2^tm1Tasa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:131146
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The third coding region was replaced with a neo cassette. The absence of transcript was confirmed by RT-PCR on lung extracts. (J:131146)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptgdr2 Mutation: 15 strains or lines available

References

• Original: J:131146 Satoh T, et al., Prostaglandin D2 plays an essential role in chronic allergic inflammation of the skin via CRTH2 receptor. J Immunol. 2006 Aug 15;177(4):2621-9
• All: 21 reference(s)