Atrnl1^tm1Gsb
Targeted Allele Detail

Summary

• Symbol: Atrnl1^tm1Gsb
• Name: attractin like 1; targeted mutation 1, Gregory S Barsh
• MGI ID: MGI:3773080
• Synonyms: Atrnl1^tar
• Gene: Atrnl1 Location: Chr19:57599466-58121775 bp, + strand Genetic Position: Chr19, 53.31 cM
• Alliance: Atrnl1^tm1Gsb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130463
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: 40 nucleotides in exon 24 were replaced with a lacZ-neo cassette, a strong splice acceptor and polyadenylation signal resulting in an alternate splicing event that excludes the transmemebrane domain encoding sequence. The authors state that this allele is likely to produce a functionally null protein. (J:130463)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atrnl1 Mutation: 72 strains or lines available

References

• Original: J:130463 Walker WP, et al., Genetic analysis of attractin homologs. Genesis. 2007 Dec;45(12):744-56
• All: 1 reference(s)