Hoxb1^tm1(cre)Og
Targeted Allele Detail

Summary

• Symbol: Hoxb1^tm1(cre)Og
• Name: homeobox B1; targeted mutation 1, Stephen O'Gorman
• MGI ID: MGI:3773272
• Synonyms: B1-cre, Hoxb1^cre
• Gene: Hoxb1 Location: Chr11:96256578-96259082 bp, + strand Genetic Position: Chr11, 59.86 cM
• Alliance: Hoxb1^tm1(cre)Og page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:100238
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutations: Insertion, Intragenic deletion
• Hoxb1^tm1(cre)Og expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Hoxb1 (MGI:96182)

• The open reading frame was replaced with an in-frame cre open reading frame. (J:100238, J:131060)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Hoxb1 (mouse) Summary of all recombinase alleles driven by Hoxb1. Comparative matrix view of recombinase activities Alliance mouse Hoxb1 gene page

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hoxb1 Mutation: 24 strains or lines available

References

• Original: J:100238 O'Gorman S, Second branchial arch lineages of the middle ear of wild-type and Hoxa2 mutant mice. Dev Dyn. 2005 Sep;234(1):124-31
• All: 6 reference(s)