Tg(Hbb/Hoxa2-cre)1Fmr
Transgene Detail

Summary

• Symbol: Tg(Hbb/Hoxa2-cre)1Fmr
• Name: transgene insertion 1, Filippo M Rijli
• MGI ID: MGI:3773535
• Synonyms: r2-cre
• Transgene: Tg(Hbb/Hoxa2-cre)1Fmr Location: unknown
• Alliance: Tg(Hbb/Hoxa2-cre)1Fmr page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Hbb/Hoxa2-cre)1Fmr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Hoxa2 (MGI:96174)

• Mutation details: This transgene contains the beta-globin promoter fragment fused to the 2.5 kb mouse Hoxa2 rhombomere 2-specific enhancer element to drive expression of cre in rhombomere 2. This transgene allele was made with the same construct used for the generation of Tg(Hbb/Hoxa2-cre)2Fmr. (J:75130)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Hoxa2 (mouse) Summary of all recombinase alleles driven by Hoxa2. Comparative matrix view of recombinase activities Alliance mouse Hoxa2 gene page
User Notes:	Additional information submitted by the research community Additional information submitted by the research community The creator of this transgene line states that cre expression was progressively lost after many generations of crossings. (J:309626)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:75130 Ren SY, et al., A Hoxa2 mutant conditional allele generated by Flp- and Cre-mediated recombination. Genesis. 2002 Feb;32(2):105-8
• All: 5 reference(s)