Glipr1^tm1Tt
Targeted Allele Detail

Summary

• Symbol: Glipr1^tm1Tt
• Name: GLI pathogenesis related 1; targeted mutation 1, Timothy C Thompson
• MGI ID: MGI:3773696
• Gene: Glipr1 Location: Chr10:111821353-111838536 bp, - strand Genetic Position: Chr10, 59.98 cM, cytoband D1
• Alliance: Glipr1^tm1Tt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:131419
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 and 2 were replaced with a puromycin resistance cassette. Authors state that this is a null allele. (J:131419)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Glipr1^tm1Tt

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Glipr1 Mutation: 17 strains or lines available

References

• Original: J:131419 Li L, et al., Glioma pathogenesis-related protein 1 exerts tumor suppressor activities through proapoptotic reactive oxygen species-c-Jun-NH2 kinase signaling. Cancer Res. 2008 Jan 15;68(2):434-43
• All: 2 reference(s)