Tg(tetO-Prkar1a*x2as)1Stra
Transgene Detail

Summary

• Symbol: Tg(tetO-Prkar1a*x2as)1Stra
• Name: transgene insertion 1, Constantine A Stratakis
• MGI ID: MGI:3773697
• Transgene: Tg(tetO-Prkar1a*x2as)1Stra Location: unknown
• Alliance: Tg(tetO-Prkar1a*x2as)1Stra page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence, Knockdown)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: The tetracycline responsive promoter drives the expression of an antisense sequence for exon 2 of Prkar1a. (J:94953)

Disease models

Expression

In Structures Affected by this Mutation:

11 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(tetO-Prkar1a*x2as)1Stra

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:94953 Griffin KJ, et al., Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors. Cancer Res. 2004 Dec 15;64(24):8811-5
• All: 3 reference(s)