Lsamp^tm1Afpi
Targeted Allele Detail

Summary

• Symbol: Lsamp^tm1Afpi
• Name: limbic system-associated membrane protein; targeted mutation 1, Aurea Fugazzola Pimenta
• MGI ID: MGI:3773703
• Gene: Lsamp Location: Chr16:39804723-42002042 bp, + strand Genetic Position: Chr16, 28.26 cM, cytoband B5
• Alliance: Lsamp^tm1Afpi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:131383
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Part of exon 2 and intron 2 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on cerebellum extracts. (J:131383)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lsamp Mutation: 26 strains or lines available

References

• Original: J:131383 Catania EH, et al., Genetic deletion of Lsamp causes exaggerated behavioral activation in novel environments. Behav Brain Res. 2008 Apr 9;188(2):380-90
• All: 1 reference(s)