E2f7^tm1.1Gle
Targeted Allele Detail

Summary

• Symbol: E2f7^tm1.1Gle
• Name: E2F transcription factor 7; targeted mutation 1.1, Gustavo Leone
• MGI ID: MGI:3773722
• Gene: E2f7 Location: Chr10:110581300-110623245 bp, + strand Genetic Position: Chr10, 57.74 cM
• Alliance: E2f7^tm1.1Gle page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:131292
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Germ-line, cre-mediated recombination was used to remove exon 4. The absence of expression was confirmed by real-time RT-PCR. (J:131292)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any E2f7 Mutation: 32 strains or lines available

References

• Original: J:131292 Li J, et al., Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development. Dev Cell. 2008 Jan;14(1):62-75
• All: 8 reference(s)