Gper1^tm1Cwan
Targeted Allele Detail

Summary

• Symbol: Gper1^tm1Cwan
• Name: G protein-coupled estrogen receptor 1; targeted mutation 1, Chunhe Wang
• MGI ID: MGI:3773753
• Synonyms: GPERKO
• Gene: Gper1 Location: Chr5:139408906-139413555 bp, + strand Genetic Position: Chr5, 78.58 cM, cytoband G1
• Alliance: Gper1^tm1Cwan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:131313
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 3 was replaced with a neo cassette. The absence of transcript was confirmed by RT-PCR on heart liver and kidney extracts. (J:131313)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gper1 Mutation: 30 strains or lines available

References

• Original: J:131313 Wang C, et al., GPR30 Contributes to Estrogen-Induced Thymic Atrophy. Mol Endocrinol. 2008 Mar;22(3):636-48
• All: 30 reference(s)