Cadps2^tm1Bros
Targeted Allele Detail

Summary

• Symbol: Cadps2^tm1Bros
• Name: Ca2+-dependent activator protein for secretion 2; targeted mutation 1, Nils Brose
• MGI ID: MGI:3774018
• Gene: Cadps2 Location: Chr6:23262772-23839420 bp, - strand Genetic Position: Chr6, 10.57 cM
• Alliance: Cadps2^tm1Bros page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:131212
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 5 was replaced with a floxed neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:131212)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cadps2 Mutation: 86 strains or lines available

References

• Original: J:131212 Jockusch WJ, et al., CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins. Cell. 2007 Nov 16;131(4):796-808
• All: 13 reference(s)