Alkbh1^tm1.1Lpkn
Targeted Allele Detail

Summary

• Symbol: Alkbh1^tm1.1Lpkn
• Name: alkB homolog 1, histone H2A dioxygenase; targeted mutation 1.1, Steven M Lipkin
• MGI ID: MGI:3774031
• Synonyms: Alkbh1^-
• Gene: Alkbh1 Location: Chr12:87474847-87490609 bp, - strand Genetic Position: Chr12, 41.65 cM
• Alliance: Alkbh1^tm1.1Lpkn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:131022
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 3 was removed by germ-line, cre-mediated recombination. The absence of protein product was confirmed by western blot analysis. (J:131022)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Alkbh1 Mutation: 19 strains or lines available

References

• Original: J:131022 Pan Z, et al., Impaired placental trophoblast lineage differentiation in Alkbh1(-/-) mice. Dev Dyn. 2008 Feb;237(2):316-27
• All: 1 reference(s)