Fbln2^tm1Chu
Targeted Allele Detail

Summary

• Symbol: Fbln2^tm1Chu
• Name: fibulin 2; targeted mutation 1, Mon-Li Chu
• MGI ID: MGI:3774118
• Gene: Fbln2 Location: Chr6:91189442-91249522 bp, + strand Genetic Position: Chr6, 40.42 cM, cytoband D-E
• Alliance: Fbln2^tm1Chu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130362
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neo cassette was inserted after codon 282. The absences of transcript and protein were confirmed, respectively, by northern and western blot analysis. (J:130362)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fbln2 Mutation: 52 strains or lines available

References

• Original: J:130362 Sicot FX, et al., Fibulin-2 is dispensable for mouse development and elastic fiber formation. Mol Cell Biol. 2008 Feb;28(3):1061-7
• All: 8 reference(s)