Olig2^tm1(cre)Tmj
Targeted Allele Detail

Summary

• Symbol: Olig2^tm1(cre)Tmj
• Name: oligodendrocyte transcription factor 2; targeted mutation 1, Thomas M Jessell
• MGI ID: MGI:3774124
• Synonyms: olig2-cre, Olig2::Cre
• Gene: Olig2 Location: Chr16:91022345-91025565 bp, + strand Genetic Position: Chr16, 52.6 cM
• Alliance: Olig2^tm1(cre)Tmj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130378
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutations: Insertion, Intragenic deletion
• Olig2^tm1(cre)Tmj expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Olig2 (MGI:1355331)

• Exon 2 was replaced with the cre open reading frame. (J:130378)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Olig2 (mouse) Summary of all recombinase alleles driven by Olig2. Alliance mouse Olig2 gene page

Disease models

Expression

In Mice Carrying this Mutation:

20 assay results 7 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Olig2 Mutation: 46 strains or lines available

References

• Original: J:130378 Dessaud E, et al., Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism. Nature. 2007 Nov 29;450(7170):717-20
• All: 79 reference(s)