Rtn4r^tm1Gogo
Targeted Allele Detail

Summary

• Symbol: Rtn4r^tm1Gogo
• Name: reticulon 4 receptor; targeted mutation 1, Joseph A Gogos
• MGI ID: MGI:3774128
• Gene: Rtn4r Location: Chr16:17945506-17970272 bp, + strand Genetic Position: Chr16, 11.23 cM, cytoband B1
• Alliance: Rtn4r^tm1Gogo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130368
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 of the gene locus was replaced with a self excising selection cassette containing a neomycin resistance gene. After germline transmission, the cassette was removed leaving a loxP site in place of exon 2. Gene inactivation was confirmed by RT-PCR of brain RNA. (J:130368)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rtn4r Mutation: 24 strains or lines available

References

• Original: J:130368 Hsu R, et al., Nogo Receptor 1 (RTN4R) as a Candidate Gene for Schizophrenia: Analysis Using Human and Mouse Genetic Approaches. PLoS One. 2007;2(11):e1234
• All: 2 reference(s)