A^y-Jkn
Spontaneous Allele Detail

Summary

• Symbol: A^y-Jkn
• Name: nonagouti; dominant yellow
• MGI ID: MGI:3774267
• Synonyms: A^y-Jkn1
• Gene: a Location: Chr2:154792519-154892932 bp, + strand Genetic Position: Chr2, 76.83 cM
• Alliance: A^y-Jkn page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Spontaneous (Constitutively active)
• Mutation: Other
• Mutation details: A spontaneous mutation fusing the promoter and 5'-UTR of Raly to the agouti gene leads to constitutive expression of the agouti gene. Details will be reported in a manuscript currently in preparation by PS Budd and IJ Jackson. (J:129904)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any a Mutation: 463 strains or lines available

References

• Original: J:129904 Jackson IJ, et al., Humanized MC1R transgenic mice reveal human specific receptor function. Hum Mol Genet. 2007 Oct 1;16(19):2341-8
• All: 2 reference(s)