Tg(Pdx1-Ffar1)AHeed
Transgene Detail

Summary

• Symbol: Tg(Pdx1-Ffar1)AHeed
• Name: transgene insertion A, Helena Edlund
• MGI ID: MGI:3774304
• Synonyms: Ipf1/GPR40
• Transgene: Tg(Pdx1-Ffar1)AHeed Location: unknown
• Alliance: Tg(Pdx1-Ffar1)AHeed page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Pdx1-Ffar1)AHeed expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ffar1 (MGI:2684079)

• Pdx1 drives the expression of Ffar1 in beta cells. (J:129843)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Lines A and B were produced with 100 and 20 copies of the transgene, respectively. Line A was chosen as the representative line.

References

• Original: J:129843 Steneberg P, et al., The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse. Cell Metab. 2005 Apr;1(4):245-58
• All: 1 reference(s)