Kcnk9^tm1.1Daba
Targeted Allele Detail

Summary

• Symbol: Kcnk9^tm1.1Daba
• Name: potassium channel, subfamily K, member 9; targeted mutation 1.1, Douglas A Bayliss
• MGI ID: MGI:3774332
• Synonyms: TASK-3^-
• Gene: Kcnk9 Location: Chr15:72372938-72418189 bp, - strand Genetic Position: Chr15, 33.46 cM
• Alliance: Kcnk9^tm1.1Daba page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130850
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 2 was removed by germ-line, cre-mediated recombination. The absence of transcript was confirmed by in situ hybridization and qRT-PCR on brain tissue. (J:130850)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnk9 Mutation: 17 strains or lines available

References

• Original: J:130850 Mulkey DK, et al., TASK channels determine pH sensitivity in select respiratory neurons but do not contribute to central respiratory chemosensitivity. J Neurosci. 2007 Dec 19;27(51):14049-58
• All: 16 reference(s)