Avil^{tm1(ALPP)Fawa}
Targeted Allele Detail

Summary

• Symbol: Avil^{tm1(ALPP)Fawa}
• Name: advillin; targeted mutation 1, Fan Wang
• MGI ID: MGI:3774413
• Synonyms: Advillin^PLAP, Avil^AP, Avil^hPLAP
• Gene: Avil Location: Chr10:126836578-126856863 bp, + strand Genetic Position: Chr10, 74.48 cM, cytoband D3
• Alliance: Avil^{tm1(ALPP)Fawa} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130971
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The open reading frame for human placental alkaline phosphatase and a floxed neo cassette was knocked into exon 2. The absence of transcript expression was confirmed by in situ hybridization. This is a null allele. (J:130971)

Expression

In Mice Carrying this Mutation:	71 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Avil Mutation: 47 strains or lines available

References

• Original: J:130971 Hasegawa H, et al., Analyzing somatosensory axon projections with the sensory neuron-specific Advillin gene. J Neurosci. 2007 Dec 26;27(52):14404-14
• All: 7 reference(s)