Tg(Pax7-cre/ERT2)1Cbm
Transgene Detail

Summary

• Symbol: Tg(Pax7-cre/ERT2)1Cbm
• Name: transgene insertion 1, Carmen Birchmeier
• MGI ID: MGI:3774422
• Synonyms: Pax7^CreERT2, Tg(Pax7-cre/ESR1)1Cbm, Tg(Pax7-cre/ESR1)1Jejo
• Transgene: Tg(Pax7-cre/ERT2)1Cbm Location: unknown
• Alliance: Tg(Pax7-cre/ERT2)1Cbm page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Pax7-cre/ERT2)1Cbm expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Pax7

• Mutation details: This transgene contains the Pax7 promoter driving the expression of a cre/ESR1 (ERT2) fusion and an IRES-EGFP cassette inserted at the translation initiation ATG in exon 2 in the dorsal neural tube. (J:130251)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pax7 (species not specified) Summary of all recombinase alleles driven by Pax7. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Four transgenic lines were created and the one with the highest recombination rate in the spinal cord was selected.

References

• Original: J:130251 Hori K, et al., A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Genes Dev. 2008 Jan 15;22(2):166-78
• All: 3 reference(s)