Tg(KRT14-Snai1)1Efu
Transgene Detail

Summary

• Symbol: Tg(KRT14-Snai1)1Efu
• Name: transgene insertion 1, Elaine Fuchs
• MGI ID: MGI:3774670
• Synonyms: K14-Snail, K14-Snail[HA] Tg
• Transgene: Tg(KRT14-Snai1)1Efu Location: unknown
• Alliance: Tg(KRT14-Snai1)1Efu page

Tg(KRT14-Snai1)1Efu/0 mice are small, have short tails and flaky skin, and exhibit epidermal hyperproliferation

Show the 2 phenotype image(s) involving this allele.

Transgene origin

• Strain of Origin: CD-1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT14-Snai1)1Efu expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Snai1 (MGI:98330)

• Mutation details: This transgene expresses an HA-tagged Snai1 (Snail) gene under the control of the keratin 14 promoter in the epidermis. (J:97750)

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:97750 Jamora C, et al., A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis. PLoS Biol. 2005 Jan;3(1):e11
• All: 7 reference(s)