S100a10^tm1Pggd
Targeted Allele Detail

Summary

• Symbol: S100a10^tm1Pggd
• Name: S100 calcium binding protein A10 (calpactin); targeted mutation 1, Paul Greengard
• MGI ID: MGI:3775204
• Synonyms: p11^-
• Gene: S100a10 Location: Chr3:93462424-93471952 bp, + strand Genetic Position: Chr3, 40.51 cM, cytoband F1-F2
• Alliance: S100a10^tm1Pggd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104116
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The exon containing the ATG translation initaition site was replaced with a floxed neo cassette. The absence of transcript ws confirmed by in situ hybridization of the brain. (J:104116)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any S100a10 Mutation: 34 strains or lines available

References

• Original: J:104116 Svenningsson P, et al., Alterations in 5-HT1B receptor function by p11 in depression-like states. Science. 2006 Jan 6;311(5757):77-80
• All: 19 reference(s)