Tg(Vil1-CYP3A4)1Nki
Transgene Detail

Summary

• Symbol: Tg(Vil1-CYP3A4)1Nki
• Name: transgene insertion 1, The Netherlands Cancer Institute
• MGI ID: MGI:3775624
• Transgene: Tg(Vil1-CYP3A4)1Nki Location: unknown
• Alliance: Tg(Vil1-CYP3A4)1Nki page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• The mouse villin promoter was used to drive expression of human CYP3A4 in the small intestine. (J:127366)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:127366 van Herwaarden AE, et al., Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism. J Clin Invest. 2007 Nov;117(11):3583-92
• All: 3 reference(s)